A current link to all Coller lab publications can be found at Pubmed here



Quantitative tRNA-sequencing uncovers metazoan tissue-specific tRNA regulation. Nature Comm

The Ccr4-Not complex monitors the translating ribosome for codon optimality. Science

Codon and amino acid content are associated with mRNA stability in mammalian cells. PLoS One


Regulation of MicroRNA Machinery and Development by Interspecies S-Nitrosylation. Cell


Acetylation of cytidine in messenger RNA promotes translation efficiency. Cell

Attenuated codon optimality contributes to neural-specific mRNA decay in Drosophila. Cell Reports

Translation elongation and mRNA stability are coupled through the ribosomal A-site. RNA

mRNA Deadenylation Is Coupled to Translation Rates by the Differential Activities of Ccr4-Not Nucleases. Mol Cell


Short poly(A) tails are a conserved feature of highly expressed genes. Nature Struct Molec Biol.


The DEAD-box helicase Dhh1p couples mRNA decay and translation by monitoring codon optimality. Cell

Co-translational mRNA decay by microRNAs. eLife

The deadenylase components Not2p, Not3p, and Not5p promote mRNA decapping. RNA


KLF15 establishes the landscape of diurnal expression in the heart. Cell Reports

Codon optimality is a major determinant of mRNA stability. Cell


Translation of small open reading frames within unannotated RNA transcripts in Saccharomyces cerevisiae. Cell Reports


The DEAD-box protein DHH1 promotes decapping by slowing ribosome movement. PLoS Biol.

A novel decapping pathway for long non-coding RNAs regulates inducible genes. Mol Cell


A novel origin for granulovacuolar degeneration in aging and Alzheimer's disease: parallels to stress granules. Lab Investig.

A quantitative assay for measuring mRNA decapping by splinted ligation reverse transcription polymerase chain reaction: qSL-RT-PCR. RNA


Nonsense-mediated mRNA decapping occurs on polyribosomes in Saccharomyces cerevisiae. Nature SMB


Co-translational mRNA decay in Saccharomyces cerevisiae. Nature 2009


Microtubule disruption stimulates P-body formation. RNA


Neuronal RNA granules and cytoplasmic processing bodies are similar in composition and function. Neuron


General Translational Repression by Activators of mRNA Decapping. Cell

Crystal structure of DEAD box helicase, Dhh1p. RNA


The yeast Apq12 protein affects nucleocytoplasmic mRNA transport. RNA


The DEAD box helicase, Dhh1p, functions in mRNA decapping and interacts with both the decapping and deadenylase complexes. RNA


Multiple portions of poly (A) binding protein stimulate translation in vivo through a poly (A)-independent mechanism. EMBO J.


mRNA stabilization by poly(A) binding protein is independent of a poly (A) tail and requires translation. Genes Dev


Tethered function assays using 3’UTRs. Methods 2002

Eukaryotic mRNA decapping. Annu Rev Biochem. 2004

The many routes to regulating mRNA translation. Genome Biol. 2006

Tethered function assays: An adaptable approach to study RNA regulatory proteins. Methods Enzymol. 2007

Analysis of mRNA decay in Saccharomyces cerevisiae. Methods Enzymol. 2008.

RNA research in the Rustbelt. RNA Biology, 2009

Eukaryotic RNases and their partners in RNA degradation and biogenesis. Enzymes Vol 2013

Method for measuring mRNA decay rates in Saccharomyces cerevisiae. Methods Enzymol. 2013

Polyribosome analysis for determining mRNA and ribosome association in Saccharomyces cerevisiae. Methods Enzymol. 2013

RNA in unexpected places: long noncoding RNAs function in a variety of cellular contexts. Nature Rev Molec Cell Biol. 2013

Pausing on polysomes: May way for elongation in translational control. Cell, 2015

Codon optimality, bias and usage in translation and mRNA decay. Nature Rev Molec Cell Biol.2017

Structural and molecular mechanisms for the control of eukaryotic 5’-3’ mRNA decay. Nat Struct Mol Biol. 2018

tRNA metabolism and neurodevelopmental disorders, Annu Rev Genomics Hum Genet. 2019


Alternate endings - A new story for mRNA decapping. Mol Cell. 2010

What comes first: translational repression or mRNA degradation? The deepening mystery of microRNA function. Cell Res. 2010

The DHH1/RCKp54 family of helicases: An ancient family of proteins that promote translational silencing. Biochimica et Biophysica Acta, 2013

The Molecular Biology of Non-coding RNA. Springer Sci Press 2013

PAN-orama - Three convergent views of a eukaryotic deadenylase. Nature Struct Molec Biol. 2014

A Method that Will Captivate U. Mol Cell. 2015

A Universal Code for mRNA stability? Trends Genetics. 2016

Decapping in 3-D. Nature Struct Molec Biol. 2016