A current link to all Coller lab publications can be found at Pubmed here



Tethered mRNA amplifier: A novel appraoch to increase protein expression. Methods Mol. Biol.


tRNA therapeutics for genetic diseases Nat Rev Drug Discov.

Computational design of mRNA vaccines. Vaccine


Oligodendrocyte differentiation alters tRNA modifications and codon optimality-mediated mRNA decay. Nature Comm.

Development of a tethered mRNA amplifier to increase protein expression. Biotechnol J.

Roles of mRNA poly(A) tails in regulation of eukaryotic gene expression. Nature Reviews

Suppression of premature transcription termination leads to reduced mRNA isoform diversity and neurodegeneration. Neuron

Codon optimality-mediated mRNA degradation: Linking translational elongation to mRNA stability. Mol Cell


Quantitative tRNA-sequencing uncovers metazoan tissue-specific tRNA regulation. Nature Comm

The Ccr4-Not complex monitors the translating ribosome for codon optimality. Science

Codon and amino acid content are associated with mRNA stability in mammalian cells. PLos One


Regulation of MicroRNA Machinery and Development by Interspecies S-Nitrosylation. Cell

tRNA metabolism and neurodevelopmental disorders. Annu Rev Genomics Hum Genet.


Acetylation of cytidine in messenger RNA promotes translation efficiency. Cell

Attenuated codon optimality contributes to neural-specific mRNA decay in Drosophila. Cell Reports

Translation elongation and mRNA stability are coupled through the ribosomal A-site. RNA

mRNA Deadenylation Is Coupled to Translation Rates by the Differential Activities of Ccr4-Not Nucleases. Mol Cell

Structural and molecular mechanisms for the control of eukaryotic 5’-3’ mRNA decay. Nat Struct Mol Biol.


Short poly(A) tails are a conserved feature of highly expressed genes. Nature Struct. Molec. Biol.

Codon optimality, bias and usage in translation and mRNA decay. Nature Reviews


The DEAD-box helicase Dhh1p couples mRNA decay and translation by monitoring codon optimality. Cell

Co-translational mRNA decay by microRNAs. eLife

The deadenylase components Not2p, Not3p, and Not5p promote mRNA decapping. RNA

A Universal Code for mRNA stability? Trends Genetics

mRNA Decapping in 3-D. Nature Struct Molec Biol.


KLF15 establishes the landscape of diurnal expression in the heart. Cell Reports

Codon optimality is a major determinant of mRNA stability. Cell

Pausing on polysomes: May way for elongation in translational control. Cell

A Method that Will Captivate U. Mol Cell.


Translation of small open reading frames within unannotated RNA transcripts in Saccharomyces cerevisiae. Cell Reports

PAN-orama - Three convergent views of a eukaryotic deadenylase. Nature Struct Molec Biol.


Eukaryotic RNases and their partners in RNA degradation and biogenesis. Enzymes

Method for measuring mRNA decay rates in Saccharomyces cerevisiae. Methods Enzymol.

Polyribosome analysis for determining mRNA and ribosome association in Saccharomyces cerevisiae. Methods Enzymol.

RNA in unexpected places: long noncoding RNAs function in a variety of cellular contexts. Nature Reviews

The DHH1/RCKp54 family of helicases: An ancient family of proteins that promote translational silencing. Biochimica et Biophysica Acta

The Molecular Biology of Non-coding RNA. Springer Sci Press


The DEAD-box protein DHH1 promotes decapping by slowing ribosome movement. PLoS Biol.

A novel decapping pathway for long non-coding RNAs regulates inducible genes. Mol Cell


A novel origin for granulovacuolar degeneration in aging and Alzheimer's disease: parallels to stress granules. Lab Investig.

A quantitative assay for measuring mRNA decapping by splinted ligation reverse transcription polymerase chain reaction: qSL-RT-PCR. RNA


Nonsense-mediated mRNA decapping occurs on polyribosomes in Saccharomyces cerevisiae. Nature SMB

Alternate endings - A new story for mRNA decapping. Mol Cell.

What comes first: translational repression or mRNA degradation? The deepening mystery of microRNA function. Cell Res.


Co-translational mRNA decay in Saccharomyces cerevisiae. Nature 2009


Methods to determine mRNA half-life in Saccharomyes cerevisiae. Methods Enzymol.


Microtubule disruption stimulates P-body formation. RNA

Tethered function assays: An adaptable approach to study RNA regulatory proteins. Methods Enzymol.


Neuronal RNA granules and cytoplasmic processing bodies are similar in composition and function. Neuron

The many routes to regulating mRNA translation. Genome Biol.


General Translational Repression by Activators of mRNA Decapping. Cell

Crystal structure of DEAD box helicase, Dhh1p. RNA


The yeast Apq12 protein affects nucleocytoplasmic mRNA transport. RNA

Eukaryotic mRNA decapping. Annu Rev Biochem.


Tethered function assays using 3’UTRs. Methods


The DEAD box helicase, Dhh1p, functions in mRNA decapping and interacts with both the decapping and deadenylase complexes. RNA


Multiple portions of poly (A) binding protein stimulate translation in vivo through a poly (A)-independent mechanism. EMBO J.


mRNA stabilization by poly(A) binding protein is independent of a poly (A) tail and requires translation. Genes Dev